(-)-Huperzine A

CAS No. 102518-79-6

(-)-Huperzine A ( Huperzine A )

Catalog No. M10115 CAS No. 102518-79-6

A naturally occurring sesquiterpene alkaloid that a reversible and selective inhibitor of acetylcholinesterase (AChE).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 39 In Stock
25MG 74 In Stock
50MG 133 In Stock
100MG 237 In Stock
200MG 441 In Stock
500MG 707 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    (-)-Huperzine A
  • Note
    Research use only, not for human use.
  • Brief Description
    A naturally occurring sesquiterpene alkaloid that a reversible and selective inhibitor of acetylcholinesterase (AChE).
  • Description
    A naturally occurring sesquiterpene alkaloid that a reversible and selective inhibitor of acetylcholinesterase (AChE); has been used for improving memory, cognitive and behavioral function in Alzheimer's disease; activates Wnt/β-catenin signaling and enhances the nonamyloidogenic pathway in an Alzheimer transgenic mouse model.Alzheimer's Disease Approved
  • Synonyms
    Huperzine A
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    AChE
  • Recptor
    AChE (G4 form)
  • Research Area
    Neurological Disease
  • Indication
    Alzheimer Disease

Chemical Information

  • CAS Number
    102518-79-6
  • Formula Weight
    242.32
  • Molecular Formula
    C15H18N2O
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C(N1)C=CC2=C1C[C@H]3/C([C@@]2(N)CC(C)=C3)=C\C
  • Chemical Name
    5,9-Methanocycloocta[b]pyridin-2(1H)-one, 5-amino-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-, (5R,9R,11E)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Burshtein G, et al. Planta Med. 2013 Mar;79(3-4):259-65.
2. Wang J, et al. J Neurosci Res. 2010 Mar;88(4):807-15.
3. Wang CY, et al. Neuropsychopharmacology. 2011 Apr;36(5):1073-89.
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